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Home > Product > Antibody > Cleaved PARP Monoclonal Antibody(M4)

Cleaved PARP Monoclonal Antibody(M4)

Cleaved PARP Monoclonal Antibody(M4)

Product Summary

Size: 20ul,50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB

Product Summary

Size: 20ul,50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB

Product overview

Full product name

Poly (ADP-ribose) polymerase 1

Code

BT-MCA0346

Host

Mouse

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Monoclonal

Immunogen

Synthetic Peptide of Cleaved PARP

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage

-20°C for one year

Background

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 14225591

Synonyms

PARP1; ADPRT; PPOL; Poly (ADP-ribose) polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly(ADP-ribose) synthase 1

Research area

Epigenetics and nuclear signaling; Cell biology; Metabolism; Cancer

Target protein

PARP1

Recommended dilution

Application Dilution
WB 1:1000-3000

Images

Western blot analysis of 1) Jurkat, 2) Hela diluted at 1:2000.

Protocols

Customer reviews and Q&As

No reviews
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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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