Product overview
Full product name
Code
Host
Isotype
Size
Clonality
Immunogen
Purification
Concentration
Formulation
Storage
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis.
Uniprot accession
Molecular weight
Gene ID
Synonyms
Research area
Target protein
Recommended dilution
| Application | Dilution |
|---|---|
| WB | 1:1000 - 1:2000 |
Images
Protocols
Customer reviews and Q&As
