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Home > Product > Antibody > IL-10 Monoclonal Antibody

IL-10 Monoclonal Antibody

IL-10 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, ELISA

Product overview

Full product name

Interleukin-10

Code

BT-MCA0764

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human IL-10 expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Purified antibody in PBS containing 0.03% sodium azide.

Storage

-20°C for one year

Background

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 3586

Synonyms

IL10; Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF

Research area

Cancer; Immunology

Target protein

IL10

Recommended dilution

Application Dilution
ELISA 1:10000
WB 1:500 - 1:2000

Images

Western Blot analysis using IL-10 Monoclonal antibody against IL-10 recombinant protein.

Protocols

Customer reviews and Q&As

No reviews
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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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