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Home > Product > Antibody > N-CoR Monoclonal Antibody

N-CoR Monoclonal Antibody

N-CoR Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Nuclear receptor corepressor 1

Code

BT-MCA0932

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of N-CoR (aa1-192) expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 9611

Synonyms

NCOR1; KIAA1047; Nuclear receptor corepressor 1; N-CoR; N-CoR1

Research area

Epigenetics and Nuclear Signaling; Signal Transduction; Cancer; Metabolism

Target protein

NCOR1

Recommended dilution

Application Dilution
ELISA 1:10000
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using N-CoR Monoclonal antibody against truncated Trx-N-CoR recombinant protein (1).
Immunohistochemistry analysis of paraffin-embedded human cerebra (left) and breast carcinoma tissue (right), showing nuclear location with DAB staining using N-CoR Monoclonal antibody.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

Add to Cart

Lead time: Within one week

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