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Home > Product > Antibody > PARP-1 Monoclonal Antibody

PARP-1 Monoclonal Antibody

PARP-1 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, FCM, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, FCM, ELISA

Product overview

Full product name

Poly (ADP-ribose) polymerase 1

Code

BT-MCA0990

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Synthetic peptide of human PARP-1, conjugated to KLH.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 142

Synonyms

PARP1; ADPRT; PPOL; Poly (ADP-ribose) polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly(ADP-ribose) synthase 1

Research area

Epigenetics and nuclear signaling

Target protein

PARP1

Recommended dilution

Application Dilution
ELISA 1:10000
FC 1:200 - 1:400
WB 1:500 - 1:2000

Images

Western Blot analysis using PARP-1 Monoclonal antibody against Jurkat (1) K562 (2) HeLa (3) Raji (4)THP-1 (5) and SW620 (6) cell lysate.
Flow cytometric analysis of Jurkat cells using PARP-1 Monoclonal antibody (green) and negative control (purple).

Protocols

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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