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Home > Product > Antibody > PRMT6 Monoclonal Antibody

PRMT6 Monoclonal Antibody

PRMT6 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, IF, ICC

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Mouse,Rat

Applications: WB, IHC-p, IF, ICC

Product overview

Full product name

Protein arginine N-methyltransferase 6

Code

BT-MCA1066

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant human PRMT6 protein fragments expressed in E.coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Storage

-20°C for one year

Background

The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 55170; Mouse: 99890

Synonyms

PRMT6; HRMT1L6; Protein arginine N-methyltransferase 6; Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6; Histone-arginine N-methyltransferase PRMT6

Research area

Epigenetics and nuclear signaling

Target protein

PRMT6

Recommended dilution

Application Dilution
IF 1:100 - 1:500
IHC 1:500 - 1:1000
WB 1:1000 - 1:2000

Images

Western Blot analysis using PRMT6 Monoclonal antibody against HeLa, 293T cell lysate.
Immunofluorescence analysis of HeLa cells using PRMT6 Monoclonal antibody.

Protocols

Customer reviews and Q&As

No reviews
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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

Add to Cart

Lead time: Within one week

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