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Home > Product > Antibody > PYK2 Monoclonal Antibody

PYK2 Monoclonal Antibody

PYK2 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Protein-tyrosine kinase 2-beta

Code

BT-MCA1077

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of PYK2 (aa815-997) expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity t

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 2185

Synonyms

PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro

Research area

Signal transduction; Metabolism; Cancer

Target protein

PTK2B

Recommended dilution

Application Dilution
ELISA 1:10000
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using PYK2 Monoclonal antibody against Raji (1) PMA induced THP-1 (2) Jurkat (3) and Ramos (4) cell lysate.
Immunohistochemistry analysis of paraffin-embedded human Tonsil tissues with AEC staining using PYK2 Monoclonal antibody.

Protocols

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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