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Home > Product > Antibody > Caspase 2 Rabbit Polyclonal Antibody

Caspase 2 Rabbit Polyclonal Antibody

Caspase 2 Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat, Mouse

Applications: WB, ELISA

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB, ELISA

Product overview

Full product name

Caspase 2

Code

BT-AP06905

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from human Caspase 2 (p12| Cleaved-Ala348)

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

alternative products:Isoforms differ in the N- and C-termini|Catalytic activity:Strict requirement for an Asp residue at P1| with 316-asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-|-.|Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.|PTM:The mature protease can process its own propeptide| but not that of other caspases.|Belongs to the peptidase C14A family.|Contains 1 CARD domain.|subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers| each one formed by a p18 subunit and a p12 subunit. Interacts with LRDD.|tissue specificity:Expressed at higher levels in the embryonic lung| liver and kidney than in the heart and brain. In adults| higher level expression is seen in the placenta| lung| kidney| and pancreas than in the heart| brain| liver and skeletal muscle.|

Uniprot accession

Molecular weight

49720

Gene ID

Human: 835; Mouse: 12366; Rat: 64314

Synonyms

Caspase 2 ;p12; Cleaved-Ala348; Caspase-2; CASP-2; EC 3.4.22.55; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1; Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12;

Research area

Cancer; Cell biology; Metabolism

Target protein

CASP2

Recommended dilution

Application Dilution
WB 1: 1000 - 1: 2000
ELISA 1: 5000 - 1: 20000

Protocols

Customer reviews and Q&As

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Product size

Price

  • 100ul

    $275.00

  • 50ul

    $180.00

  • 20ul

    $108.00

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Lead time: Within one week

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