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Home > Product > Antibody > Stat3 Polyclonal Antibody

Stat3 Polyclonal Antibody

Stat3 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, IHC-p, IF

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-p, IF

Product overview

Full product name

Signal transducer and activator of transcription 3

Code

BT-AP01664

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Recombinant Protein of Stat3

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage

-20°C for 1 year

Background

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors| STAT family members are phosphorylated by the receptor associated kinases| and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs| EGF| IL5| IL6| HGF| LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli| and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper

Uniprot accession

Gene ID

Human: 6774

Synonyms

Signal transducer and activator of transcription 3; STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor

Research area

Epigenetics and nuclear signaling; Cancer; Signal transduction; Microbiology; Stem cells; Cardiovascular; Developmental biology

Target protein

STAT3

Recommended dilution

Application Dilution
WB 1: 1000 - 1: 2000
IHC 1: 200 - 500

Images

Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma using Stat3 Polyclonal Antibody.
Western blot analysis of Hela using Stat3 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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