M-CSF Receptor(Phospho-Tyr546) Rabbit Polyclonal Antibody

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Home > Product > Antibody > M-CSF Receptor(Phospho-Tyr546) Rabbit Polyclonal Antibody

M-CSF Receptor(Phospho-Tyr546) Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

Product overview

Full product name

M-CSF Receptor

Code

BT-AP11191

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized phosho peptide around human M-CSF Receptor (Tyr546)

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene is the receptor for colony stimulating factor 1| a cytokine which controls the production| differentiation| and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants.

Uniprot accession

Human:;Mouse:;Rat:;

Gene ID

Human: 1436; Mouse: 12978

Synonyms

M-CSF Receptor ;Tyr546; Macrophage colony-stimulating factor 1 receptor; CSF-1 receptor; CSF-1-R; CSF-1R; M-CSF-R; EC 2.7.10.1; Proto-oncogene c-Fms; CD antigen CD115

Research area

Cancer; Cardiovascular; Cell biology; Immunology; Signal transduction; Stem cells

Target protein

CSF1R

Recommended dilution

Application	Dilution
WB	1: 1000 - 1: 2000

Protocols

> Protocol Booklet

Customer reviews and Q&As

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Datasheet

Product size

Price

100ul

$275.00
50ul

$180.00
20ul

$108.00

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Lead time: Within one week

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