Tel:86 021 3100 7137

Publish and get free product : share with us your publications using BT LAB product and get free products.
Home > Product > Antibody > PKA C(Phospho-Thr197) Rabbit Polyclonal Antibody

PKA C(Phospho-Thr197) Rabbit Polyclonal Antibody

PKA C(Phospho-Thr197) Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

Product overview

Full product name

PKA C

Code

BT-AP11958

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized phosho peptide around human PKA C (Thr197)

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes one of the catalytic subunits of protein kinase A| which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits| in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes| including differentiation| proliferation| and apoptosis. Constitutive activation of this gene caused either by somatic mutations| or genomic duplications of regions that include this gene| have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Altern

Uniprot accession

Gene ID

Human: 5566; Mouse: 18747

Synonyms

PKA C ;Thr197 ; cAMP-dependent protein kinase catalytic subunit alpha; PKA C-alpha; EC 2.7.11.11

Research area

Cancer; Cardiovascular; Signal transduction

Target protein

PRKACA

Recommended dilution

Application Dilution
WB 1: 1000 - 1: 2000

Images

Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°C overnight

Protocols

Customer reviews and Q&As

No reviews
No reviews

Product size

Price

  • 100ul

    $275.00

  • 50ul

    $180.00

  • 20ul

    $108.00

Add to Cart

Lead time: Within one week

We are continuously updating our Antibody catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

Newsletter

Sign up

Newsletter

Sign up