Tel:86 021 3100 7137

Publish and get free product : share with us your publications using BT LAB product and get free products.
Home > Product > Antibody > PLC gamma1(Phospho-Ser1248) Rabbit Polyclonal Antibody

PLC gamma1(Phospho-Ser1248) Rabbit Polyclonal Antibody

PLC gamma1(Phospho-Ser1248) Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

Product overview

Full product name

PLCγ1

Code

BT-AP04182

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized phosho peptide around human PLCγ1 (Ser1248)

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene catalyzes the formation of inositol 1|4|5-trisphosphate and diacylglycerol from phosphatidylinositol 4|5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example| when activated by SRC| the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi| where it activates Ras. Also| this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Gene ID

Human: 5335; Mouse: 18803; Rat: 25738

Synonyms

PLCγ1 ;Ser1248 ; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase gamma-1; EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1

Research area

Cancer; Cardiovascular; Metabolism; Signal transduction

Target protein

PLCG1

Recommended dilution

Application Dilution
WB 1: 1000 - 1: 2000

Protocols

Customer reviews and Q&As

No reviews
No reviews

Product size

Price

  • 100ul

    $275.00

  • 50ul

    $180.00

  • 20ul

    $108.00

Add to Cart

Lead time: Within one week

We are continuously updating our Antibody catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

Newsletter

Sign up

Newsletter

Sign up