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Home > Product > Antibody > SPTA1 Rabbit Polyclonal Antibody

SPTA1 Rabbit Polyclonal Antibody

SPTA1 Rabbit Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

Product overview

Full product name

SPTA1

Code

BT-AP04870

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from human SPTA1

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton| and functions in the determination of cell shape| arrangement of transmembrane proteins| and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin| which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders| including elliptocytosis type 2| pyropoikilocytosis| and spherocytic hemolytic anemia.

Uniprot accession

Molecular weight

266090

Gene ID

Human: 6708; Mouse: 20739

Synonyms

SPTA1

Research area

Signal transduction; Cardiovascular

Target protein

SPTA1

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000

Images

Western blot analysis of lysates from Jarkat cells, primary antibody was diluted at 1:1000, 4°C overnight

Protocols

Customer reviews and Q&As

No reviews
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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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