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Home > Product > Antibody > CD11b Polyclonal Antibody

CD11b Polyclonal Antibody

CD11b Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, ELISA

Product overview

Full product name

Integrin alpha-M

Code

BT-AP14793

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human CD11b. AA range:769-818

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Molecular weight

127179

Gene ID

Human: 3684

Synonyms

Integrin alpha-M; ITGAM; CD11B; CR3A; Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b

Research area

Signal transduction; Stem cells; Neuroscience; Tags & cell markers; Immunology

Target protein

ITGAM

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
ELISA 1: 10000

Images

Western blot analysis of 293T 453 using CD11b antibody. Antibody was diluted at 1:1000. Secondary antibody was diluted at 1:20000
Western blot analysis of lysates from RAW264.7 cells, using CD11b antibody.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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