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Home > Product > Antibody > FAS-L Polyclonal Antibody

FAS-L Polyclonal Antibody

FAS-L Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat, Mouse

Applications: IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: IHC-p, IF, ELISA

Product overview

Full product name

Tumor necrosis factor ligand superfamily member 6

Code

BT-AP15531

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Synthetic peptide from human protein at AA range: 121-170

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.

Uniprot accession

Gene ID

Human: 356; Mouse: 14103

Synonyms

Tumor necrosis factor ligand superfamily member 6 ;Apoptosis antigen ligand;APTL;CD95 ligand;CD95-L;Fas antigen ligand;Fas ligand;FasL;CD antigen CD178 [Cleaved into: Tumor necrosis fac; Tumor necrosis factor ligand superfamily member 6; Apoptosis antigen ligand; APTL; CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasL; CD antigen CD178; Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form; Receptor-binding FasL ectodomain; Soluble Fas ligand; sFasL; ADAM10-processed FasL form; APL; FasL intracellular domain; FasL ICD; SPPL2A-processed FasL form; SPA;

Research area

Cancer; Cell biology; Immunology; Stem cells

Target protein

FASLG

Recommended dilution

Application Dilution
IHC-p 1: 50 - 1: 200
ELISA 1: 10000 - 1: 20000

Images

Immunohistochemical analysis of paraffin-embedded Human-colon-cancer, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded Human-colon-cancer, antibody was diluted at 1:100

Protocols

Customer reviews and Q&As

No reviews
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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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