Full product name
Heart- and neural crest derivatives-expressed protein 1
Code
BT-AP09809
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human HAND1 around the phosphorylation site of Ser98. AA range:71-120
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.
Uniprot accession
Molecular weight
23627
Gene ID
Human: 9421; Mouse: 15110; Rat: 59112
Synonyms
Heart- and neural crest derivatives-expressed protein 1; HAND1; BHLHA27; EHAND; Heart- and neural crest derivatives-expressed protein 1; Class A basic helix-loop-helix protein 27; bHLHa27; Extraembryonic tissues; heart, autonomic nervous system and neural crest derivatives-expressed protein 1; eH
Research area
Cardiovascular; Developmental biology; Epigenetics and nuclear signaling; Stem cells
Target protein
HAND1