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Home > Product > Antibody > IL-15 Polyclonal Antibody

IL-15 Polyclonal Antibody

IL-15 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat, Mouse

Applications: IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: IHC-p, IF, ELISA

Product overview

Full product name

Interleukin-15

Code

BT-AP10287

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Synthetic peptide from human protein at AA range: 111-160

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported.

Uniprot accession

Gene ID

Human: 3600; Mouse: 16168

Synonyms

Interleukin-15 ;IL-15; Interleukin-15; IL-15

Research area

Cancer; Immunology; Metabolism; Stem cells

Target protein

IL15

Recommended dilution

Application Dilution
IHC-p 1: 50 - 1: 200
ELISA 1: 10000 - 1: 20000

Images

Immunohistochemical analysis of paraffin-embedded Human-breast-cancer, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded Human-brain, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded Human-brain, antibody was diluted at 1:100

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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