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Home > Product > Antibody > Insulin Polyclonal Antibody

Insulin Polyclonal Antibody

Insulin Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC-p, IF, ELISA

Product overview

Full product name

Insulin [Cleaved into: Insulin B chain; Insulin A chain]

Code

BT-AP10406

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Synthetic peptide from human protein at AA range: 30-70

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.

Uniprot accession

Gene ID

Human: 3630; Mouse: 0

Synonyms

Insulin [Cleaved into: Insulin B chain; Insulin A chain]; Insulin [Cleaved into: Insulin B chain; Insulin A chain;

Research area

Signal transduction; Cardiovascular; Metabolism; Neuroscience; Cancer

Target protein

INS

Recommended dilution

Application Dilution
IHC-p 1: 50 - 1: 200
ELISA 1: 10000 - 1: 20000

Images

Immunohistochemical analysis of paraffin-embedded Human-pancreas, antibody was diluted at 1:100

Protocols

Customer reviews and Q&As

No reviews
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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

Add to Cart

Lead time: Within one week

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