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Home > Product > Antibody > PP1 alpha(Phospho Thr320) Polyclonal Antibody

PP1 alpha(Phospho Thr320) Polyclonal Antibody

PP1 alpha(Phospho Thr320) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC-p, IF, ELISA

Product overview

Full product name

Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

Code

BT-AP13239

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human PP1-alpha around the phosphorylation site of Thr320. AA range:281-330

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Molecular weight

37512

Gene ID

Human: 5499; Mouse: 19045; Rat: 24668

Synonyms

Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; PPP1CA; PPP1A; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; PP-1A

Research area

Cancer; Metabolism; Signal transduction

Target protein

PPP1CA

Recommended dilution

Application Dilution
IHC-p 1: 100 - 1: 300
ELISA 1: 10000

Images

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using PP1-alpha (Phospho-Thr320) Antibody. The picture on the right is blocked with the phospho peptide.
Western blot analysis of PP1-alpha (Phospho-Thr320) Antibody. The lane on the right is blocked with the PP1-alpha (Phospho-Thr320) peptide.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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