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Home > Product > Antibody > PTN13 Polyclonal Antibody

PTN13 Polyclonal Antibody

PTN13 Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat, Mouse

Applications: IHC-p, IF

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: IHC-p, IF

Product overview

Full product name

Tyrosine-protein phosphatase non-receptor type 13

Code

BT-AP13382

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from part region of human protein

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, ha

Uniprot accession

Gene ID

Human: 5783

Synonyms

Tyrosine-protein phosphatase non-receptor type 13 ;EC 3.1.3.48;Fas-associated protein-tyrosine phosphatase 1;FAP-1;PTP-BAS;Protein-tyrosine phosphatase 1E;PTP-E1;hPTPE1;Protein-tyrosine

Research area

Cancer; Cell biology; Signal transduction

Target protein

PTPN13

Recommended dilution

Application Dilution
IHC-p 1: 50 - 1: 300

Protocols

Customer reviews and Q&As

No reviews
No reviews

Product size

Price

  • 100ul

    $275.00

  • 50ul

    $180.00

  • 20ul

    $108.00

Add to Cart

Lead time: Within one week

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