Full product name
Superoxide dismutase [Mn], mitochondrial
Code
BT-AP14365
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the Internal region of human SOD-2.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Storage
-20°C for 1 year
Background
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.
Uniprot accession
Gene ID
Human: 6648
Synonyms
Superoxide dismutase [Mn], mitochondrial; SOD2; Superoxide dismutase [Mn; , mitochondrial
Research area
Signal transduction; Neuroscience; Cell biology; Metabolism; Cancer
Target protein
SOD2
