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Home > Product > Antibody > Stat2 Polyclonal Antibody

Stat2 Polyclonal Antibody

Stat2 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Signal transducer and activator of transcription 2

Code

BT-AP14534

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human STAT2. AA range:656-705

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Molecular weight

97916

Gene ID

Human: 6773

Synonyms

Signal transducer and activator of transcription 2; STAT2; Signal transducer and activator of transcription 2; p113

Research area

Epigenetics and nuclear signaling; Signal transduction; Microbiology

Target protein

STAT2

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IHC-p 1: 100 - 1: 300
ELISA 1: 5000

Images

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using STAT2 Antibody. The picture on the right is blocked with the synthesized peptide.
Western Blot analysis of various cells using Stat2 Polyclonal Antibody
Western blot analysis of lysates from HepG2, using STAT2 Antibody. The lane on the right is blocked with the synthesized peptide.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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