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Home > Product > Antibody > Anti-Covid-19 Spike mAb IgM(03FC)

Anti-Covid-19 Spike mAb IgM(03FC)

Anti-Covid-19 Spike mAb IgM(03FC)

Product Summary

Size: 100ug,1mg

Clonality: Monoclonal

Host: Mouse

Reactivity:Covid-19

Applications: WB,ELISA

Product Summary

Size: 100ug,1mg

Clonality: Monoclonal

Host: Mouse

Reactivity: Covid-19

Applications: WB,ELISA

Product overview

Full product name

SARS-CoV-2 Spike, 2019-nCoV Spike, Covid-19 Spike

Code

BT-CV00006

Host

Mouse

Isotype

IgM

Size

100ug,1mg

Clonality

Monoclonal

Immunogen

The recombinant SARS-CoV-2 (2019-nCoV) Spike Protein S

Purification

The antibody was affinity-purified from 293T expression by affinity-chromatography using specific immunogen.

Concentration

2mg/mL

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

Coronaviruses (CoVs) infect human and animals and cause varieties of diseases, including respiratory, enteric, renal, and neurological diseases. CoV uses its spike protein to recognize ACE2 as its receptors and mediate membrane fusion and virus entry into host cells(PMID: 32221306). Each monomer of trimeric S protein is about 180 kDa, and contains two subunits, S1 and S2,S1 recognizes and binds to host receptors, and subsequent conformational changes in S2 facilitate fusion between the viral envelope and the host cell membrane(PMID: 19198616). Although the amino acid sequences of the S-glycoprotein were found to be different between the various HCoV, the structures showed high similarity, but the best 3D structural overlap shared by SARS-CoV and SARS-CoV-2, consistent with the shared ACE2 predicted receptor (PMID: 32522207). The spike protein of CoVs can be a target for vaccine and therapeutic development (PMID: 19198616).

Synonyms

SARS-CoV-2 Spike, 2019-nCoV Spike, Covid-19 Spike

Research area

Others

Target protein

SARS-CoV-2 S, 2019-nCoV S, Covid-19 S

Recommended dilution

Application Dilution
ELISA 1:5000 - 1:100000
WB 1:1000 - 1:10000

Protocols

Customer reviews and Q&As

No reviews
No reviews

Product size

Price

  • 100ug

    $630.00

  • 1mg

    $1850.00

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Lead time: Within one week

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