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Product > Antibody > PHB Monoclonal Antibody
PHB Monoclonal Antibody
PHB Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5H7
Host: Mouse
Reactivity:Human, Mouse, Rat, Monkey
Applications: WB,IHC,ICC,FCM
Product Summary
Size:
50μL
Clonality: 5H7
Host: Mouse
Reactivity: Human,Mouse,Rat,Monkey
Applications: WB,IHC,ICC,FCM
Product overview
Code
BT-MCA3263
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5H7
Immunogen
Purified recombinant fragment of human PHB expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
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