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Product > Antibody > TDGF1 Monoclonal Antibody
TDGF1 Monoclonal Antibody
TDGF1 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 3A6
Host: Mouse
Reactivity:Human
Applications:
Product Summary
Size:
50μL
Clonality: 3A6
Host: Mouse
Reactivity: Human
Applications:
Product overview
Code
BT-MCA3391
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
3A6
Immunogen
Purified recombinant fragment of human TDGF1 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects.The cripto gene is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. It could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.Tissue specificity: Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts.
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