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Product > Antibody > AURKA Monoclonal Antibody
AURKA Monoclonal Antibody
AURKA Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 4G10
Host: Mouse
Reactivity:Human, Monkey, Rat
Applications: WB,IHC
Product Summary
Size:
50μL
Clonality: 4G10
Host: Mouse
Reactivity: Human,Monkey,Rat
Applications: WB,IHC
Product overview
Code
BT-MCA3057
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
4G10
Immunogen
Purified recombinant fragment of human AURKA expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.
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