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Product > Antibody > MSI2 Monoclonal Antibody
MSI2 Monoclonal Antibody
MSI2 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 2C11
Host: Mouse
Reactivity:Human
Applications: WB,IHC
Product Summary
Size:
50μL
Clonality: 2C11
Host: Mouse
Reactivity: Human
Applications: WB,IHC
Product overview
Code
BT-MCA3122
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
2C11
Immunogen
Purified recombinant fragment of human MSI2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous; detected at low levels.
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