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Product > Antibody > ZBTB16 Monoclonal Antibody
ZBTB16 Monoclonal Antibody
ZBTB16 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5B3
Host: Mouse
Reactivity:Human
Applications: WB,ICC
Product Summary
Size:
50μL
Clonality: 5B3
Host: Mouse
Reactivity: Human
Applications: WB,ICC
Product overview
Code
BT-MCA3212
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5B3
Immunogen
Purified recombinant fragment of human ZBTB16 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. Tissue specificity: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.
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