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Product > Antibody > TLR2 Monoclonal Antibody
TLR2 Monoclonal Antibody
TLR2 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 2D6
Host: Mouse
Reactivity:Human
Applications: WB
Product Summary
Size:
50μL
Clonality: 2D6
Host: Mouse
Reactivity: Human
Applications: WB
Product overview
Code
BT-MCA3437
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
2D6
Immunogen
Purified recombinant fragment of human TLR2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
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