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Product > Antibody > ISL1 Monoclonal Antibody
ISL1 Monoclonal Antibody
ISL1 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 1H9
Host: Mouse
Reactivity:Human
Applications: IHC,ICC
Product Summary
Size:
50μL
Clonality: 1H9
Host: Mouse
Reactivity: Human
Applications: IHC,ICC
Product overview
Code
BT-MCA2604
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
1H9
Immunogen
Purified recombinant fragment of human ISL1 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young.
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