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Product > Antibody > TBX5 Monoclonal Antibody
TBX5 Monoclonal Antibody
TBX5 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 7B11
Host: Mouse
Reactivity:Human
Applications: WB
Product Summary
Size:
50μL
Clonality: 7B11
Host: Mouse
Reactivity: Human
Applications: WB
Product overview
Code
BT-MCA3066
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
7B11
Immunogen
Purified recombinant fragment of TBX5 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
TBX5, also known as T-box 5. It is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The TBX5 protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.
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