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Product > Antibody > NANOG Monoclonal Antibody
NANOG Monoclonal Antibody
NANOG Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 1E6C4
Host: Mouse
Reactivity:Human
Applications: WB,ICC
Product Summary
Size:
50μL
Clonality: 1E6C4
Host: Mouse
Reactivity: Human
Applications: WB,ICC
Product overview
Code
BT-MCA3280
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
1E6C4
Immunogen
Purified recombinant fragment of NANOG (aa20-166) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
NANOG: Nanog homeobox. Entrez Protein NP_079141. Nanog is a divergent homeodomain protein that directs pluripotency and differentiation of undifferentiated embryonic stem cells. Nanog mRNA is present in pluripotent mouse and human cell lines, and absent from differentiated cells. Human Nanog protein shares 52% overall amino acid identity with the mouse protein and 85% identity in the homeodomain. Human Nanog maps to gene locus 12p13.31, whereas mouse Nanog maps to gene loci 6 F2. Murine embryonic Nanog expression is detected in the inner cell mass of the blastocyst. High levels of human Nanog expression were detected by Northern analysis in the undifferentiated N-Tera embryonal carcinoma cell line.
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