IRF3 Monoclonal Antibody

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Home > Product > Antibody > IRF3 Monoclonal Antibody

IRF3 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse, Rat

Applications: WB,IHC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,FCM

Product overview

Code

BT-MCA4335

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human IRF3 (AA: 1-150) expressed in HEK293-6e cells supernatant.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7.

Uniprot accession

Q14653:;

Molecular weight

47.2kDa

Gene ID

3661

Synonyms

IIAE7

Research area

Immunology

Target protein

IRF3

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
IHC-p	1:200 - 1:1000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using IRF3 mAb against human IRF3 (AA: 1-150) recombinant protein. (Expected MW is 47.4 kDa)

Western blot analysis using IRF3 mouse mAb against THP-1 (1), Hela (2), A549 (3), MCF-7 (4), K562 (5), Jurkat (6) and A431 (7) cell lysate.

Flow cytometric analysis of Hela cells using IRF3 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using IRF3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded human colon cancer tissues using IRF3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissues using IRF3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using IRF3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded mouse kidney tissues using IRF3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded mouse brain tissues using IRF3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded rat kidney tissues using IRF3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded rat brain tissues using IRF3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded rabbit kidney tissues using IRF3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded rabbit brain tissues using IRF3 mouse mAb with DAB staining.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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