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Home > Product > Antibody > PLIN3 Monoclonal Antibody

PLIN3 Monoclonal Antibody

PLIN3 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB,ICC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB,ICC,FCM

Product overview

Code

BT-MCA2378

Host

Mouse

Isotype

Mouse IgG2a

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human PLIN3 expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Molecular weight

47kDa

Gene ID

10226

Synonyms

PP17;TIP47;M6PRBP1

Research area

Signal transduction

Target protein

PLIN3

Recommended dilution

Application Dilution
WB 1:500 - 1:2000
ICC 1:100 - 1:500
FCM 1:200 - 1:400

Images

Western blot analysis using PLIN3 mouse mAb against THP-1 (1), HepG2 (2), K562 (3) and Hela (4) cell lysate.
Immunofluorescence analysis of Hela cells using PLIN3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Flow cytometric analysis of Hela cells using PLIN3 mouse mAb (green) and negative control (red).

Protocols

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Product size

Price

  • 100μL

    $320.00

  • 50μL

    $220.00

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Lead time: Within one week

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