XRCC1 Monoclonal Antibody

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Blood coagulation
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Home > Product > Antibody > XRCC1 Monoclonal Antibody

XRCC1 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Others

Applications: WB,IHC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Others

Applications: WB,IHC,FCM

Product overview

Code

BT-MCA3367

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human XRCC1 (AA:1-150) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Uniprot accession

P18887:;

Molecular weight

69.5kDa

Gene ID

7515

Synonyms

RCC;SCAR26

Research area

Epigenetics and Nuclear Signaling

Target protein

XRCC1

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
IHC-p	1:200 - 1:1000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using XRCC1 mAb against human XRCC1 (AA:1-150) recombinant protein. (Expected MW is 42.5 kDa)

Western blot analysis using XRCC1 mAb against HEK293-6e (1) and human XRCC1 (AA:1-150)-hIgGFc transfected HEK293-6e (2) cell lysate.

Western blot analysis using XRCC1 mouse mAb against Hela (1), Jurkat (2),k562 (3),SK-OV-3 (4), and COS-7 (5) cell lysate.

Flow cytometric analysis of Jurkat cells using XRCC1 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded bladder Cancer tissues using Jurkat mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using Jurkat mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using Jurkat mouse mAb with DAB staining.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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