BT-MCA4425

Mouse

Mouse IgG2b

100μL,50μL

Monoclonal

Purified recombinant fragment of human CD338 (AA: extra mix) expressed in E. Coli.

Purified antibody in PBS with 0.05% sodium azide

Store at 4°C short term. Aliquot and store at -20°C long term.

The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.

Q9UNQ0:;

75kDa

9429

MRX;MXR;ABCP;BCRP;BMDP;MXR1;ABC15;BCRP1;ABCG2;GOUT1;MXR-1;CDw338;UAQTL1;EST157481

Others

CD338