IGF1R Monoclonal Antibody

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Blood coagulation
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Home > Product > Antibody > IGF1R Monoclonal Antibody

IGF1R Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Others

Applications: WB,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Others

Applications: WB,FCM

Product overview

Code

BT-MCA4754

Host

Mouse

Isotype

Mouse IgG2a

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human IGF1R (AA: extra(741-935)) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Uniprot accession

P08069:;

Molecular weight

154.8kDa

Gene ID

3480

Synonyms

IGFR;CD221;IGFIR;JTK13

Research area

Others

Target protein

IGF1R

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using IGF1R mAb against human IGF1R (AA: extra(741-935)) recombinant protein. (Expected MW is 25.2 kDa)

Western blot analysis using IGF1R mAb against HEK293-6e (1) and IGF1R (AA: extra(741-935))-hIgGFc transfected HEK293-6e (2) cell lysate.

Western blot analysis using IGF1R mouse mAb against NIH3T3 (1), cell lysate.

Flow cytometric analysis of HepG2 cells using IGF1R mouse mAb (green) and negative control (red).

Flow cytometric analysis of Lovo cells using IGF1R mouse mAb (green) and negative control (red).

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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