BT-MCA2016

Mouse

Mouse IgG1

100μL,50μL

Monoclonal

Purified recombinant fragment of human MAPK7 (AA: 411-556) expressed in E. Coli.

Purified antibody in PBS with 0.05% sodium azide.

Store at 4°C short term. Aliquot and store at -20°C long term.

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

Q13164:;

88.4kDa

5598

BMK1;ERK4;ERK5;PRKM7

Others

MAPK7