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Home > Product > Antibody > AMPK Gamma1 Polyclonal Antibody

AMPK Gamma1 Polyclonal Antibody

AMPK Gamma1 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

AMPKgamma1 Antibody

Code

BT-AP00422

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human PRKAG1. AA range:10-59

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

The protein encoded by PRKAG1 (protein kinase AMP-activated non-catalytic subunit gamma 1) is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Uniprot accession

Molecular weight

37579

Gene ID

Human: 5571; Mouse: 19082; Rat: 25520

Synonyms

PRKAG1; 5'-AMP-activated protein kinase subunit gamma-1; AMPK gamma1; AMPK subunit gamma-1; AMPKg

Research area

Cardiovascular; Cardiovascular

Target protein

PRKAG1

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
ELISA 1: 5000

Images

Western Blot analysis of 293 cells using AMPKγ1 Polyclonal Antibody cells nucleus.
Western blot analysis of the lysates from HT-29 cells using PRKAG1 antibody.

Protocols

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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