c-Fms Polyclonal Antibody

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Home > Product > Antibody > c-Fms Polyclonal Antibody

c-Fms Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, ELISA

Product overview

Full product name

c-Fms Antibody

Code

BT-AP01722

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human M-CSF Receptor. AA range:781-830

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Colony stimulating factor 1 receptor encoded by CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations inCSF1R have been associated with a predisposition to myeloid malignancy. The first intron of CSF1R contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

107984

Gene ID

Human: 1436; Mouse: 12978

Synonyms

CSF1R; FMS; Macrophage colony-stimulating factor 1 receptor; CSF-1 receptor; CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD antigen CD115

Research area

Cardiovascular

Target protein

CSF1R

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 10000

Images

Western Blot analysis of various cells using c-Fms Polyclonal Antibody diluted at 1:500

Western blot analysis of lysates from 293 cells, treated with LPS 100ng/ml 30', using M-CSF Receptor Antibody. The lane on the right is blocked with the synthesized peptide.

Protocols

> Protocol Booklet

Customer reviews and Q&As

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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