Cleaved-Thrombin APII (R327) Polyclonal Antibody

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OneStep ELISA kit
Primacu ELISA kit
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Bioquímicos
Proteínas recombinantes

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Coagulación sanguínea
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Home > Product > Antibody > Cleaved-Thrombin APII (R327) Polyclonal Antibody

Cleaved-Thrombin APII (R327) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB, ELISA

Product overview

Full product name

Cleaved-Thrombin APII (R327) Antibody

Code

BT-AP01966

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human THRB. AA range:278-327

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants.

Uniprot accession

Human:;Mouse:;

Molecular weight

70037

Gene ID

Human: 2147

Synonyms

F2; Prothrombin; Coagulation factor II

Research area

Cardiovascular

Target protein

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 20000

Images

Western blot analysis of lysates from Jurkat cells, treated with etoposide 25uM 24H, using THRB (AP2,Cleaved-Arg327) Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using Cleaved-Thrombin APII (R327) Polyclonal Antibody

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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