Clock Polyclonal Antibody

Producto

OneStep ELISA kit
Primacu ELISA kit
Anticuerpos
Bioquímicos
Proteínas recombinantes

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Servicios de ensayo ELISA personalizados
Cotización a granel

Área de investigación

Coagulación sanguínea
Metabolismo
Cáncer
Microbiología
Cardiovascular
Neurociencia
Biología Celular
Transducción de señales
Biología del desarrollo
Células madre
Epigenéticay señalización nuclear
Etiquetas y marcadores de celda
Inmunología

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Home > Product > Antibody > Clock Polyclonal Antibody

Clock Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, ELISA

Product overview

Full product name

Clock Antibody

Code

BT-AP01990

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human Clock. AA range:241-290

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Clock circadian regulator encoded by CLOCK plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Polymorphisms in CLOCK may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

95304

Gene ID

Human: 9575; Mouse: 12753; Rat: 60447

Synonyms

CLOCK; BHLHE8; KIAA0334; Circadian locomoter output cycles protein kaput; hCLOCK; Class E basic helix-loop-helix protein 8; bHLHe8

Research area

Neuroscience

Target protein

CLOCK

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC	1: 100 - 1: 300
ELISA	1: 20000

Images

Western blot analysis of lysates from HUVEC cells, using Clock Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using Clock Polyclonal Antibody

Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using Clock Antibody. The picture on the right is blocked with the synthesized peptide.

Protocols

> Protocol Booklet

Customer reviews and Q&As

No reviews

Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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