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Home > Product > Antibody > DSCR 1 Polyclonal Antibody

DSCR 1 Polyclonal Antibody

DSCR 1 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

DSCR 1 Antibody

Code

BT-AP02740

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human RCAN1. AA range:201-250

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Regulator of calcineurin 1 encoded by RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of RCAN1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

22637

Gene ID

Human: 1827; Mouse: 54720; Rat: 266766

Synonyms

RCAN1; ADAPT78; CSP1; DSC1; DSCR1; Calcipressin-1; Adapt78; Down syndrome critical region protein 1; Myocyte-enriched calcineurin-interacting protein 1; MCIP1; Regulator of calcineurin 1

Research area

Neuroscience

Target protein

RCAN1

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
ELISA 1: 10000

Images

Western Blot analysis of HeLa cells using DSCR 1 Polyclonal Antibody diluted at 1:1000
Western Blot analysis of various cells using DSCR 1 Polyclonal Antibody diluted at 1:1000
Western blot analysis of RCAN1 Antibody. The lane on the right is blocked with the RCAN1 peptide.
Western blot analysis of the lysates from HT-29 cells using RCAN1 antibody.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request
We are continuously updating our Antibody catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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