Factor VIII Polyclonal Antibody

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OneStep ELISA kit
Primacu ELISA kit
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Bioquímicos
Proteínas recombinantes

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Servicios de ensayo ELISA personalizados
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Coagulación sanguínea
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Home > Product > Antibody > Factor VIII Polyclonal Antibody

Factor VIII Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC-p, ELISA

Product overview

Full product name

Factor VIII Antibody

Code

BT-AP03124

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human Factor VIII. AA range:2161-2210

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

F8 encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. F8 produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. DefectsF8 results in hemophilia A, a common recessive X-linked coagulation disorder.

Uniprot accession

Human:;Mouse:;

Molecular weight

267009

Gene ID

Human: 2157; Mouse: 14069

Synonyms

F8; F8C; Coagulation factor VIII; Antihemophilic factor; AHF; Procoagulant component

Research area

Cardiovascular

Target protein

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC	1: 100 - 1: 300
ELISA	1: 10000

Images

Western Blot analysis of various cells using Factor VIII Polyclonal Antibody

Western Blot analysis of HuvEc cells using Factor VIII Polyclonal Antibody

Western blot analysis of lysates from HUVEC cells, using Factor VIII Antibody. The lane on the right is blocked with the synthesized peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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