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Home > Product > Antibody > Fliz1 Polyclonal Antibody

Fliz1 Polyclonal Antibody

Fliz1 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-p, ELISA

Product overview

Full product name

Fliz1 Antibody

Code

BT-AP03268

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human ZC3H8. AA range:81-130

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

ZC3H8 is a Protein Coding gene. Zinc finger CCCH domain-containing protein 8 acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5-AGGTCTC-3 sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis. Among its related pathways are Gene Expression and RNA Polymerase II Transcription Initiation And Promoter Clearance. GO annotations related to this gene include poly (A) RNA binding and sequence-specific DNA binding. An important paralog of this gene is ZC3H4.

Uniprot accession

Molecular weight

33576

Gene ID

Human: 84524

Synonyms

ZC3H8; ZC3HDC8; Zinc finger CCCH domain-containing protein 8

Research area

Epigenetics and Nuclear Signaling

Target protein

ZC3H8

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IHC 1: 100 - 1: 300
ELISA 1: 40000

Images

Western Blot analysis of various cells using Fliz1 Polyclonal Antibody cells nucleus.
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ZC3H8 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from HepG2 cells, using ZC3H8 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from COLO205 cells using ZC3H8 antibody.

Protocols

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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