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Home > Product > Antibody > Ku-70 (Acetyl Lys331) Polyclonal Antibody

Ku-70 (Acetyl Lys331) Polyclonal Antibody

Ku-70 (Acetyl Lys331) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

Ku-70 (Acetyl Lys331) Antibody

Code

BT-AP04887

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized Acetyl-peptide derived from human Ku70 around the Acetylation site of Lys331. AA range:291-340

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Uniprot accession

Molecular weight

69843

Gene ID

Human: 2547; Mouse: 14375

Synonyms

XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent

Research area

Epigenetics and Nuclear Signaling

Target protein

XRCC6

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
ELISA 1: 20000

Images

Western Blot analysis of 4T1 cells using Acetyl-Ku-70 (K331) Polyclonal Antibody. Secondary antibody was diluted at 1:20000
Western blot analysis of lysate from 4T1 cells, using Ku70 (Acetyl-Lys331) Antibody.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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