Phospho-4E-BP1 (T70) Polyclonal Antibody

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OneStep ELISA kit
Primacu ELISA kit
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Bioquímicos
Proteínas recombinantes

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Servicios de ensayo ELISA personalizados
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Coagulación sanguínea
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Home > Product > Antibody > Phospho-4E-BP1 (T70) Polyclonal Antibody

Phospho-4E-BP1 (T70) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: IHC-p, ELISA

Product overview

Full product name

Phospho-4E-BP1 (T70) Antibody

Code

BT-PHS01077

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human 4E-BP1 around the phosphorylation site of Thr70. AA range:36-85

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

EIF4EBP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Uniprot accession

Human:;Mouse:;

Molecular weight

12449

Gene ID

Human: 1978

Synonyms

EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I

Research area

Epigenetics and Nuclear Signaling; Metabolism

Target protein

EIF4EBP1

Recommended dilution

Application	Dilution
IHC	1: 100 - 1: 300
ELISA	1: 5000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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