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Home > Product > ELISA Kit > Human Reticulon-4 Receptor, RTN4R ELISA Kit

Human Reticulon-4 Receptor, RTN4R ELISA Kit

Human Reticulon-4 Receptor, RTN4R ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 9.69ng/L

Detection range: 20-3500ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 9.69ng/L

Detection range: 20-3500ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Reticulon-4 Receptor

Code

E6081Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

9.69ng/L

Detection range

20-3500ng/L

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Receptor for RTN4, OMG and MAG (PubMed: 12037567, PubMed: 12068310, PubMed: 12426574, PubMed: 12089450, PubMed: 16712417, PubMed: 18411262, PubMed: 12839991, PubMed: 19052207). Functions as receptor for the sialylated gangliosides GT1b and GM1 (PubMed: 18411262). Besides, functions as receptor for chondroitin sulfate proteoglycans (By similarity). Can also bind heparin (By similarity). Intracellular signaling cascades are triggered via the coreceptor NGFR (PubMed: 12426574). Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed: 16712417, PubMed: 22325200). Mediates axonal growth inhibition (PubMed: 12839991, PubMed: 19052207, PubMed: 28892071). Plays a role in regulating axon regeneration and neuronal plasticity in the adult central nervous system. Plays a role in postnatal brain development. Required for normal axon migration across the brain midline and normal formation of the corpus callosum. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated via interaction with MAG. Acts in conjunction with RTN4 and LINGO1 in regulating neuronal precursor cell motility during cortical development. Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed: 22325200).

UniProt accession

MASS(Da)

50,708

GeneID

65078

Synonyms

NgR;Nogo receptor;Nogo-66 receptor;Reticulon-4 receptor;RTN 4R;RTN4R

Gene names

RTN4R

Research area

Others

Target protein

RTN4R

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E6081Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
2000ng/L 2.262 2.224 2.19
2.186
1000ng/L 1.473 1.498 1.464
1.524
500ng/L 0.631 0.705 0.671
0.779
250ng/L 0.404 0.418 0.384
0.432
125ng/L 0.189 0.161 0.127
0.133
0ng/L 0.04 0.034 0
0.028

Precision

We measured random samples of E6081Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 1159.5 42.99 3.7
Intra-Assay 2 18 548.1 26.05 4.8
Intra-Assay 3 18 352.6 17.78 5

Protocols

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  • Size

    Code

    Price

  • 48T

    E6081Hu

    $320.00

  • 96T

    E6081Hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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