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Home > Product > Antibody > HDAC5/9(Phospho Ser259/220) Polyclonal Antibody

HDAC5/9(Phospho Ser259/220) Polyclonal Antibody

HDAC5/9(Phospho Ser259/220) Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Histone deacetylase 5/9

Code

BT-AP00844

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human HDAC5 around the phosphorylation site of Ser259. AA range:225-274

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Molecular weight

121992

Gene ID

Human: 10014/9734; Mouse: 79221

Synonyms

Histone deacetylase 5/9; HDAC5; KIAA0600; Histone deacetylase 5; HD5; Antigen NY-CO-9; HDAC9; HDAC7; HDAC7B; HDRP; KIAA0744; MITR; Histone deacetylase 9; HD9; Histone deacetylase 7B; HD7; HD7b; Histone deacetylase-related protein; MEF2-interacting transcription rep

Research area

Cardiovascular; Epigenetics and nuclear signaling; Stem cells

Target protein

HDAC5

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IHC-p 1: 100 - 1: 300
ELISA 1: 10000

Images

Western Blot analysis of HepG2 cells using Phospho-HDAC5/9 (S259/220) Polyclonal Antibody diluted at 1:2000
Western Blot analysis of COLO HELA 293T cells using Phospho-HDAC5/9 (S259/220) Polyclonal Antibody diluted at 1:2000
Western blot analysis of lysates from HepG2 cells, using HDAC5 (Phospho-Ser259) Antibody. The lane on the right is blocked with the phospho peptide.

Protocols

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Product size

Price

  • 100ul

    $275.00

  • 50ul

    $180.00

  • 20ul

    $108.00

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Lead time: Within one week

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