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Product > Antibody > SNAI2 Monoclonal Antibody
SNAI2 Monoclonal Antibody
SNAI2 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 2H5
Host: Mouse
Reactivity:Human
Applications:
Product Summary
Size:
50μL
Clonality: 2H5
Host: Mouse
Reactivity: Human
Applications:
Product overview
Code
BT-MCA4755
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
2H5
Immunogen
Purified recombinant fragment of human SNAI2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity.The tumor suppressor protein p53 induces Slug expression in gamma-irradiated cells; Slug protects damaged cells from apoptosis by repressing p53-induced transcription of the proapoptotic Bcl-2 family protein Puma. Mutations in this gene may be associated with sporatic cases of neural tube defects.
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